摘要 |
The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells. |
申请人 |
INTERNATIONAL STEM CELL CORPORATION |
发明人 |
TUROVETS, NIKOLAY;AGAPOVA, LARISA;SEMECHKIN, ANDREY;JANUS, JEFFREY, D. |