发明名称 |
METHOD FOR IN-VITRO MONITORING OF NEURONAL DISORDERS AND USE THEREOF |
摘要 |
<p>The present invention relates to methods and neuronal cellular preparations allowing monitoring intracellular and transcellular molecular events on both short and long timescales in an ex vivo neuronal network of intact post-mitotic neurons. In particular, the invention relates to methods, kits, genetically engineered neuronal cells, preparations and uses thereof allowing the ex vivo monitoring of early neuronal disease-related changes in neuronal network behavior.</p> |
申请公布号 |
EP2591356(A1) |
申请公布日期 |
2013.05.15 |
申请号 |
EP20110748724 |
申请日期 |
2011.07.11 |
申请人 |
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) |
发明人 |
GIUGLIANO, MICHELE;LUTHI-CARTER, RUTH;MARKRAM, HENRY;GAMBAZZI, LUCA;GOEKCE, OZGUEN |
分类号 |
G01N33/483;G01N33/50 |
主分类号 |
G01N33/483 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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