发明名称 Dihydropyrimidone amides as P2X7 modulators
摘要 Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4, R5, Ra and Rb are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.
申请公布号 US8435990(B2) 申请公布日期 2013.05.07
申请号 US20100847129 申请日期 2010.07.30
申请人 BROTHERTON-PLEISS CHRISTINE E.;CAROON JOAN MARIE;LOPEZ-TAPIA FRANCISCO JAVIER;WALKER KEITH ADRIAN MURRAY;ROCHE PALO ALTO LLC 发明人 BROTHERTON-PLEISS CHRISTINE E.;CAROON JOAN MARIE;LOPEZ-TAPIA FRANCISCO JAVIER;WALKER KEITH ADRIAN MURRAY
分类号 C07D239/22;A61K31/513;C07D403/12 主分类号 C07D239/22
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