| 发明名称 |
AMINOALKYL-SUBSTITUTED N-THIENYL BENZAMIDE DERIVATIVE |
| 摘要 |
<p>The objective of the present invention is to provide a compound having inhibitory activity against an intestinal phosphate transporter (NPT-IIb), and useful as an active ingredient in a hyperphosphatemia therapeutic agent and/or preventive. A thiophene compound represented by formula (I) may be used as a hyperphosphatemia therapeutic agent and/or preventive having NPT-IIb inhibitory activity. (In the formula, R1-6 each represent H or a lower alkyl or the like, L1-4 each represent a lower alkyl or the like, X1 represents CH2 or O, X2-3 each represent CH or N, k is 1-3, and n is 0-1.)</p> |
| 申请公布号 |
WO2013062065(A1) |
申请公布日期 |
2013.05.02 |
| 申请号 |
WO2012JP77660 |
申请日期 |
2012.10.25 |
| 申请人 |
ASTELLAS PHARMA INC. |
发明人 |
MIURA, MASANORI;KAGA, DAISUKE;WATANUKI, SUSUMU;HACHIYA, SHUNICHIRO;OKUDA, TAKAO;SATO, IPPEI;ISOMURA, MAI;TERAI, KAZUHIRO;TERADA, YOH |
| 分类号 |
C07D333/68;A61K31/381;A61K31/439;A61K31/4436;A61K31/444;A61K31/4535;A61K31/496;A61K31/506;A61K31/5377;A61P7/00;A61P13/12;A61P19/00;A61P43/00;C07D333/78;C07D333/80;C07D409/12;C07D409/14;C07D413/12;C07D417/12;C07D453/02;C07D495/04 |
主分类号 |
C07D333/68 |
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