DRUGS FOR DISEASES ASSOCIATED WITH AMYLOID beta, AND SCREENING THEREFOR

摘要

The present invention relates to the provision of drugs for the treatment or prevention of conditions, disorders, or diseases associated with amyloid beta. Provided is a method of screening for drugs for the treatment or prevention of diseases associated with amyloid beta which includes (A) a step for establishing conditions in which at least one substance selected from the group consisting of 1) exosomes, 2) neutral sphingomyelinase 2 (N-SMase2), and 3) sphingomyelin synthase 2 (SMS2) can interact with a drug candidate and (B) a step for examining the effects of the drug candidate on the substance, wherein the at least one substance serves as an indicator of whether the candidate can serve as a drug.