发明名称 |
Ube2g2 binding domain in the ubiquitin ligase gp78 and methods of use thereof |
摘要 |
The present invention features isolated nucleic acid molecules, designated G2BD nucleic acid molecules, which encode the binding site from the gp78 ubiquitin ligase that binds to the Ube2G2 ubiquitin conjugating enzyme. The invention further provides isolated G2BD proteins and fusion proteins. Still further provided are diagnostic and therapeutic methods, as well as screening assays utilizing compositions of the invention. |
申请公布号 |
US8420776(B2) |
申请公布日期 |
2013.04.16 |
申请号 |
US20050597453 |
申请日期 |
2005.04.27 |
申请人 |
WEISSMAN ALLAN;MARIANO JENNIFER;CHEN BO;TSAI YIEN CHE;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
WEISSMAN ALLAN;MARIANO JENNIFER;CHEN BO;TSAI YIEN CHE |
分类号 |
C07K14/435;C12P21/02 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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