SCREENING METHOD OF CANDIDATE MATERIAL FOR SKIN BARRIER FUNCTION RECOVERY OF ATOPIC DERMATITIS BY CONTROL OF FATTY ACID ELONGASE EXPRESSION AND CARBON CHAIN EXPRESSION

摘要

PURPOSE: A method for screening a material which recovers skin barrier function of atopic skin through controlling expression of fatty acid elongase and carbon chain is provided to detecting ceramide fatty acid and to accurately screen skin improving substances. CONSTITUTION: A method for screening a material for treating atopic dermatitis comprises: a step of identifying expression level of elongase in keratinocytes treated with candidate materials; and a step of determining a material which enhances the expression level of the elongase as a material which improves atopic dermatitis. [Reference numerals] (AA) Score; (BB) Control group;