| 发明名称 |
METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS |
| 摘要 |
A major object of the present invention is to provide a method for producing induced pluripotent stem cells with low tumorigenesis potential and high induction efficiency. The invention provides a method for producing induced pluripotent stem cells comprising the step of introducing one or more nucleic acids that facilitate expression of at least one gene selected from the group consisting of NANOG, SOX2, OCT3/4, KLF4, LIN28, and c-MYC into somatic cells.
|
| 申请公布号 |
US2013065243(A1) |
申请公布日期 |
2013.03.14 |
| 申请号 |
US201113579314 |
申请日期 |
2011.02.18 |
| 申请人 |
MORI MASAKI;ISHII HIDESHI;MIYOSHI NORIKATSU;DOKI YUICHIRO;TANEMURA MASAHIRO;NAGAI KENICHI;HOSHINO HIROMITSU;OMURA YOSHIAKI;HARAGUCHI NAOTSUGU;MIYAZAKI SUSUMU |
发明人 |
MORI MASAKI;ISHII HIDESHI;MIYOSHI NORIKATSU;DOKI YUICHIRO;TANEMURA MASAHIRO;NAGAI KENICHI;HOSHINO HIROMITSU;OMURA YOSHIAKI;HARAGUCHI NAOTSUGU;MIYAZAKI SUSUMU |
| 分类号 |
C12N5/071;C07H21/02;C07H21/04;C12N5/10;C12N15/85;C12Q1/68 |
主分类号 |
C12N5/071 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
