| 摘要 |
The present invention relates to PAS (Plasmid Acromobacter Secretion) factor mutants, particularly to a PAS factor mutant, vectors carrying the same, and processes for preparing recombinant peptides and proteins using the vectors. The vectors containing the PAS factor mutant enable to express peptides or proteins fused to the PAS factor mutant in much higher level. In addition, transmembrane proteins such as ryanodine receptor and human-origiated proteins such as calcipressin that have been known not to be expressed in conventional vector systems, can be successfully expressed by use of the PAS factor mutant. |
