COMPLEX COMPRISING WATER-SOLUBLE FRAGMENTS OF FC?RI AND COMPOSITION COMPRISING SAME FOR TREATING ALLERGIC DISEASES MEDIATED BY IGE

摘要

The present invention relates to a complex in which water-soluble fragments of FceRI, which is a receptor having a high affinity to the Fc region of immunoglobulin E (IgE), are bound with a material having biocompatibility. The complex in which the water-soluble fragments of FceRI are bound with the material having biocompatibility according to the present invention inhibits the coupling of IgE and the FceRI, which is a receptor of the IgE, so as to suppress the secretion of allergic cytokine. Thus, the complex has the effect of treating and preventing allergic diseases.