摘要 |
A genetically altered animal specimen is provided by a process comprising: identifying a gene that is desired to be altered, disrupting the gene in a gene carrier to thereby create a new DNA fragment; inserting the new DNA fragment into an embryonic cell, injecting the embryonic cell which exhibits the desired genetic alteration into an embryo, inserting the embryo into a uterus of a carrier whereby the carrier's offspring shall exhibit the desired genetic alteration, and the offspring is the genetically altered animal specimen, in this case the neurocalcin δ gene knockout mouse model.
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