摘要 |
L-ornithine can be produced by cultivating an auxotrophic mutant of Escherichia coli which requires arginine or citrulline, but not ornithine for the growth in a cultivation medium containing assimilable carbon, nitrogen sources, inorganic ions and arginine or citrulline, phosphate ion of said medium being limited to about 0.5 - 3.5 mu mole/ml, under aerobic condition.
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