| 发明名称 |
TRANSLOCATION SIGNAL FACILITATED NUCLEAR DELIVERY OF MACROMOLECULES |
| 摘要 |
Methods for introducing proteins or nucleotide sequences into the nucleus using a novel receptor-mediated delivery system. The delivery system construct includes a cell receptor-binding domain, a cytoplasmic translocation domain, and a nuclear translocation signal domain. This system can transport functional macromolecule that will act once internalized into the nucleus. |
| 申请公布号 |
WO9404696(A1) |
申请公布日期 |
1994.03.03 |
| 申请号 |
WO1993US07945 |
申请日期 |
1993.08.24 |
| 申请人 |
MILES INC. |
发明人 |
BARNETT, THOMAS, R.;DAS, RATHINDRA, C. |
| 分类号 |
C12N15/09;A61K38/00;A61K47/48;C07K14/21;C12N15/87;(IPC1-7):C12N15/87;C12N15/62;C12N15/31;C07K13/00 |
主分类号 |
C12N15/09 |
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