| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for preventing or reducing adverse side effects in patients. <P>SOLUTION: There are provided a method, composition, formulation and kit each related to acadesine, or a prodrug, analog or salt thereof and/or a blood coagulation inhibitor for preventing or reducing adverse side effects in a patient. The type of patient that may benefit includes a patient with decreased left ventricular function, a patient with a prior myocardial infarction, a patient undergoing non-vascular surgery, or a fetus during labor and delivery. In one aspect, the method comprises preventing or reducing adverse side effects in a patient decreased in left ventricular function to an ejection fraction of less than 30%, by administering the patient with an effective amount of acadesine, or a prodrug, analog or salt thereof. In an embodiment, the patient in question is an woman, optionally at an age between 65 and 95. <P>COPYRIGHT: (C)2013,JPO&INPIT |
