| 摘要 |
<p>Disclosed are a method for the preparation of 3-butoxy-2-pyrazineformamide and use thereof, specifically the use of 3-butoxy-2-pyrazineformamide, pharmaceutically acceptable salts, hydrates or solvates thereof in the preparation of anti-virus drugs. By transforming into T1105 in vivo, 3-butoxy-2-pyrazineformamide shows anti-virus activity, evidently improves oral bioavailability of T1105 and extends the duration of action of T1105 in vivo.</p> |
| 申请人 |
INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA;LI, SONG;LI, XINGZHOU;ZHONG, WU;WANG, LILI;ZHENG, ZHIBING;XIAO, JUNHAI;ZHOU, XINBO;CHEN, WEI;ZHAO, GUOMING;WANG, XIAOKUI |
发明人 |
LI, SONG;LI, XINGZHOU;ZHONG, WU;WANG, LILI;ZHENG, ZHIBING;XIAO, JUNHAI;ZHOU, XINBO;CHEN, WEI;ZHAO, GUOMING;WANG, XIAOKUI |
