The present disclosure provides an isolated or recombinant IL-23-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain specifically binds to IL-23 but does not significantly bind to an IL-12p40 subunit and does not significantly bind to an IL-23p19 subunit when they are not components of IL-23. The present disclosure also provides uses of the IL-23-binding protein.
申请公布号
AU2011282476(A1)
申请公布日期
2013.01.10
申请号
AU20110282476
申请日期
2011.07.20
申请人
CEPHALON AUSTRALIA PTY LTD
发明人
CLARKE, ADAM WILLIAM;DOYLE, ANTHONY G.;POLLARD, MATTHEW;TRAN, STEPHEN