| 摘要 |
The invention discloses a system to detect and enumerate diverse biological particles through the use of microbial spores that in the presence of a redox substrate rapidly respond to germination signals by forming discrete intracellular fluorescent formazan granules. The disclosed system enables ultrasensitive detection and enumeration of different analytes including microorganisms, viruses, nucleic acids, polypeptides, and natural or man-made particles bearing analytes.
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