发明名称 Polymer conjugate of taxane
摘要 [Problems] To provide a novel taxane derivative which can release the medicinal substance in a bioenzyme-independent manner, is expected to have an effective therapeutic efficacy, and has a water-solubility. [Means for Solving Problems] Disclosed is a polymer conjugate of a taxane, which comprises a polymer having a polyethylene glycol moiety and two or more succinic acid monoamide moieties and a taxane, wherein a carboxylate group in the polymer and an alcoholic hydroxyl group in the taxane are bound to each other via an ester bonding.
申请公布号 US8323669(B2) 申请公布日期 2012.12.04
申请号 US20070225230 申请日期 2007.03.22
申请人 KITAGAWA MASAYUKI;ISHIKAWA KEIZOU;ONDA TAKESHI;NIPPON KAYAKU KABUSHIKI KAISHA 发明人 KITAGAWA MASAYUKI;ISHIKAWA KEIZOU;ONDA TAKESHI
分类号 A61K31/77;A61K47/48;A61P35/00 主分类号 A61K31/77
代理机构 代理人
主权项
地址