发明名称 Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
摘要 <p>The invention provides methods for modulating the immune response caused by CpG-containing oligonucleotides. The methods according to the invention enable decreasing the immunostimulatory effect for antisense applications.</p>
申请公布号 EP2314693(A3) 申请公布日期 2012.11.28
申请号 EP20100010051 申请日期 2000.08.14
申请人 IDERA PHARMACEUTICALS, INC. 发明人 AGRAWAL, SUDHIR
分类号 C12N15/09;C12N15/117;A61K31/712;A61K31/7125;A61K48/00;A61P31/18;A61P37/04;A61P37/06;C07H21/00;C07H21/04 主分类号 C12N15/09
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