发明名称 |
PAPAYA MOSAIC VIRUS COMPOSITIONS AND USES THEREOF FOR STIMULATION OF THE INNATE IMMUNE RESPONSE |
摘要 |
The use of compositions comprising a papaya mosaic virus (PapMV) moiety for stimulation of the innate immune response is provided. The PapMV moiety may be papaya mosaic virus or PapMV virus-like particles (VLPs). The PapMV compositions stimulate a sufficiently strong innate immune response to provide protection against subsequent pathogen challenge or to treat an established infection. The use of PapMV compositions to protect a subject from potential infection by a pathogen, such as a viral pathogen, a bacterial pathogen or a fungal pathogen, and the use of PapMV compositions to treat an established infection, are also provided. The PapMV compositions be administered, for example, via intranasal or pulmonary routes to elicit effects within the mucosa and/or in the respiratory system. |
申请公布号 |
WO2012155261(A1) |
申请公布日期 |
2012.11.22 |
申请号 |
WO2012CA50278 |
申请日期 |
2012.05.01 |
申请人 |
FOLIA BIOTECH INC.;LECLERC, DENIS;LAMARRE, ALAIN |
发明人 |
LECLERC, DENIS;LAMARRE, ALAIN |
分类号 |
A61K39/39;A61K9/72;A61P31/00;A61P31/04;C12N7/01 |
主分类号 |
A61K39/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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