发明名称 |
PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS |
摘要 |
The present disclosure relates to the use of pantothenate compounds as a non-genetic switch for the production of heterologous acetyl-CoA derived (HACD) compounds in microbial host cells. The invention provides genetically modified microorganisms that are more stable when stored and initially cultured under reduced pantothenate concentrations, cell culture media having reduced concentrations of pantothenate compounds, and methods of producing HACD compounds using the cell culture media and the genetically engineered microorganisms of the invention.
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申请公布号 |
US2012288891(A1) |
申请公布日期 |
2012.11.15 |
申请号 |
US201213467783 |
申请日期 |
2012.05.09 |
申请人 |
MEADOWS ADAM;AMYRIS, INC. |
发明人 |
MEADOWS ADAM |
分类号 |
C12P33/20;C12P5/00;C12P5/02;C12P7/02;C12P7/04;C12P7/26;C12P7/64;C12P13/04;C12P17/02;C12P17/06;C12P17/18;C12P23/00;C12P33/00 |
主分类号 |
C12P33/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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