| 摘要 |
PURPOSE: A composition for a bio marker for determining neuronal cell debris using osteopontin is provided to remove neuronal cell debris and degenerating neurite. CONSTITUTION: A composition for a bio marker for determining neuronal cell apoptosis contains osteopontin for providing information for diagnosing nervous system diseases. The neuronal cells are CA1(cornu ammonis 1) or striatum of hippocampus. The nervous system diseases are ischemic brain injury, traumatic neural injury, stroke, CNS or PANA demyelination diseases, neuropathy, or neurodegenerative diseases. The composition is used for removing debris caused by neuronal cell apoptosis and degenerating neurite. A composition for treating nervous system diseases contains the osteopontin. The composition also contains cells transformed with a recombinant expression vector or a vector containing osteopontin gene. |
