| 发明名称 |
Substituted benzazoles and methods of their use as inhibitors of raf kinase |
| 摘要 |
New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer. |
| 申请公布号 |
US8299108(B2) |
申请公布日期 |
2012.10.30 |
| 申请号 |
US20030675927 |
申请日期 |
2003.09.29 |
| 申请人 |
AMIRI PAYMAN;FANTL WENDY;LEVINE BARRY HASKELL;POON DANIEL J.;RAMURTHY SAVITHRI;RENHOWE PAUL A.;SUBRAMANIAN SHARADHA;SUNG LEONARD;NOVARTIS AG |
发明人 |
AMIRI PAYMAN;FANTL WENDY;LEVINE BARRY HASKELL;POON DANIEL J.;RAMURTHY SAVITHRI;RENHOWE PAUL A.;SUBRAMANIAN SHARADHA;SUNG LEONARD |
| 分类号 |
A61K31/415;A61P35/00;C07D401/00;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/14;C07D413/04;C07D413/14;C07D417/12;C07D417/14;C07D453/02 |
主分类号 |
A61K31/415 |
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