| 发明名称 |
STABLE PHARMACEUTICAL LIQUID FORMULATIONS OF THE FUSION PROTEIN TNFR:FC |
| 摘要 |
The present invention relates to stable pharmaceutical liquid formulations of the fusion protein TNFR:Fc comprising different buffer systems and stabilizers. In particular, it could be demonstrated that the physical stability of TNFR:Fc is significantly improved by using a citrate buffer system and lysine as stabilizer. |
| 申请公布号 |
CA2833427(A1) |
申请公布日期 |
2012.10.26 |
| 申请号 |
CA20122833427 |
申请日期 |
2012.04.19 |
| 申请人 |
SANDOZ AG |
发明人 |
DEUTEL, BRITTA;LAUBER, THOMAS;FUERTINGER, SABINE |
| 分类号 |
A61K47/12;A61K38/00;A61K47/18 |
主分类号 |
A61K47/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
