发明名称 |
Method for proliferating cardiomyocytes using micro-RNA |
摘要 |
Disclosed are: a method for proliferating cardiomyocytes, wherein a miRNA that promotes the proliferation of cardiomyocytes is used; a vector for the treatment of heart diseases; and a pharmaceutical composition or the like for the treatment of heart diseases. Specifically disclosed are: a method for proliferating cardiomyocytes, which uses a miRNA that has a cardiomyocyte proliferation promoting action; a vector for the treatment of heart diseases, which comprises the miRNA; and a pharmaceutical composition or the like for the treatment of heart diseases, which contains the vector. The miRNA is preferably one selected from the group consisting of miR-148a, miR-148b, miR-152 and miR-373 that are mature miRNAs, precursors of the aforementioned miRNAs, and mutants and analogues of the miRNAs and the precursors. |
申请公布号 |
AU2011225115(A1) |
申请公布日期 |
2012.10.25 |
申请号 |
AU20110225115 |
申请日期 |
2011.03.11 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
KAWASHIMA, KAYOKO;KOSHIMIZU, UICHI |
分类号 |
A61K48/00;A61K31/7105;A61K31/7115;A61K31/712;A61K31/7125;A61K35/76;A61P9/00;A61P9/04;A61P9/10 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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