发明名称 PYRROLIDINE DERIVATIVES
摘要 <p>The present invention relates to compounds of formula wherein R1, R2, R3, R4, Z, and n are as defined herein or to a pharmaceutically active salt thereof. Compounds of the invention are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).</p>
申请公布号 EP2513052(A1) 申请公布日期 2012.10.24
申请号 EP20100790770 申请日期 2010.12.13
申请人 F.HOFFMANN-LA ROCHE AG 发明人 KNUST, HENNER;KOBLET, ANDREAS;NETTEKOVEN, MATTHIAS;RATNI, HASANE;RIEMER, CLAUS;VIFIAN, WALTER
分类号 C07D207/14;A61K31/5377;A61P25/18;C07D401/06;C07D403/06;C07D405/06;C07D407/04;C07D413/06;C07D417/14 主分类号 C07D207/14
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