| 摘要 |
<P>PROBLEM TO BE SOLVED: To clarify gene abnormality causing UV-sensitive syndrome, to provide a diagnostic agent and an inspective/diagnostic method of diseases accompanied with nucleotide excision repair (NER) deficiency, and to provide an improver of NER deficiency and an preventive/therapeutic agent of diseases accompanied by NER deficiency. <P>SOLUTION: There are provided a KIAA1530 gene as a causative gene of UV-sensitive syndrome, and a diagnostic agent of diseases accompanied by NER deficiency (especially UV-sensitive syndrome), the agent comprising an antibody against KIAA1530, and a nucleic acid containing a base sequence encoding KIAA1530 or a part thereof, or a nucleic acid containing a base sequence complementary to the base sequence encoding KIAA1530 or a part thereof. <P>COPYRIGHT: (C)2013,JPO&INPIT |
