METHODS FOR SCREENING INHIBITORS OF TUMOUR ASSOCIATED PROTEIN AGGREGATION

摘要

The present invention relates to the fields of protein aggregation diseases including cancer. More specifically, it concerns a screening method for identifying compounds that inhibit or disrupt co-aggregation of one or more member proteins of a disease-related protein aggregome, in particular a tumor-associated protein aggregome. Further, the invention encompasses agents and compounds identified by the screening method which can be applied to prevent or to treat protein aggregation diseases, such as cancer.