| 发明名称 |
COMPOUNDS FOR IMMUNOPROTEASOME INHIBITION. |
| 摘要 |
<p>One aspect of the invention relates to inhibitors that preferentially inhibit immunoproteasome activity over constitutive proteasome activity. In certain embodiments, the invention relates to the treatment of immune related diseases, comprising administering a compound of the invention. In certain embodiments, the invention relates to the treatment of cancer, comprising administering a compound of the invention.</p> |
| 申请公布号 |
MX2012010017(A) |
申请公布日期 |
2012.10.01 |
| 申请号 |
MX20120010017 |
申请日期 |
2011.03.01 |
| 申请人 |
ONYX THERAPEUTICS, INC.* |
发明人 |
SHENK, KEVIN D.;PARLATI, FRANCESCO;BENNETT, MARK K. |
| 分类号 |
A61K31/4045;A61K31/5375;A61P25/00;A61P29/00;A61P31/00;A61P35/00;A61P37/00;C07D209/20;C07D295/104;C07F5/04;C07K5/065 |
主分类号 |
A61K31/4045 |
| 代理机构 |
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