发明名称 Methods and applications for stitched DNA barcodes
摘要 Methods of identifying the genotypes of a plurality of single cells, wherein each cell includes a plurality of DNA barcodes, each associated with a genetic mutation or marker, are provided. In particular, methods including linking a plurality of DNA barcodes together to create a stitched barcode, amplifying the stitched barcode and sequencing the stitched barcode are provided. Also provided are methods of determining the presence of at least one genetic mutation in a population of cells.
申请公布号 US8268564(B2) 申请公布日期 2012.09.18
申请号 US20080236912 申请日期 2008.09.24
申请人 ROTH FREDERICK P.;SUZUKI YO;MELLOR JOSEPH;PRESIDENT AND FELLOWS OF HARVARD COLLEGE 发明人 ROTH FREDERICK P.;SUZUKI YO;MELLOR JOSEPH
分类号 C12P19/34 主分类号 C12P19/34
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