发明名称 |
Kinase inhibitors for preventing or treating pathogen infection and method of use thereof |
摘要 |
The present invention provides compositions and methods of use thereof to prevent and/or treat pathogenic infection. In particular, the present invention provides the use of kinase inhibitors to inhibit kinases that involve in pathogen-host cell interactions that are associated with or cause pathogenic infections, therefore, to effectively prevent and/or treat pathogenic infections with far less likely to engender resistance as compared to conventional antibiotics and anti-viral drugs. The present invention further provides the use of kinase inhibitors for the treatment of acute pathogenic infections for a short period of time to avoid toxicities that may caused by long term use of these kinase inhibitors. |
申请公布号 |
US8268809(B2) |
申请公布日期 |
2012.09.18 |
申请号 |
US20070439961 |
申请日期 |
2007.09.05 |
申请人 |
KALMAN DANIEL;BORNMANN WILLIAM;EMORY UNIVERSITY;M.D. ANDERSON CANCER CENTER |
发明人 |
KALMAN DANIEL;BORNMANN WILLIAM |
分类号 |
A01N43/00;A01N43/54;A61K31/33;A61K31/50;A61K31/505;C07D239/00;C07D239/02;C07D239/42;C07D401/00;C07D401/04;C07D403/00;C07D405/00;C07D409/00;C07D411/00;C07D413/00;C07D417/00;C07D419/00 |
主分类号 |
A01N43/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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