发明名称 NON-PEPTIDE ANTAGONISTS OF GASTRIN RELEASING PEPTIDE
摘要 This invention relates, e.g., to methods for inhibiting or stimulating an activity of an adrenomedullin (AM) or gastrin releasing peptide (GRP) peptide hormone, comprising contacting the peptide with a small molecule, non-peptide, modulatory agent of the invention. Complexes of these modulatory agents with other components, such as the peptides or blocking antibodies specific for the peptides, are also described, as are pharmaceutical compositions comprising the modulatory agents, and methods for using the modulatory agents to diagnose or treat patients.
申请公布号 US2012232107(A1) 申请公布日期 2012.09.13
申请号 US201213473507 申请日期 2012.05.16
申请人 CUTTITTA FRANK;MARTINEZ ALFREDO;THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH 发明人 CUTTITTA FRANK;MARTINEZ ALFREDO
分类号 A61K31/505;A61K31/055;A61K31/122;A61K31/194;A61K31/4196;A61K31/4245;A61K31/445;A61K31/4453;A61K31/45;A61K38/22;A61P3/10;A61P9/02;A61P9/08;A61P9/10;A61P11/00;A61P35/00;G01N33/74 主分类号 A61K31/505
代理机构 代理人
主权项
地址