发明名称 |
CRYSTALLINE PEPTIDE EPOXY KETONE PROTEASE INHIBITORS AND THE SYNTHESIS OF AMINO ACID KETO-EPOXIDES |
摘要 |
The invention relates to crystalline peptide kyto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones are stereoselectively converted to the desired keto epoxides. |
申请公布号 |
UA99630(C2) |
申请公布日期 |
2012.09.10 |
申请号 |
UA20100005277 |
申请日期 |
2008.10.03 |
申请人 |
ONYX THERAPEUTICS, INC. |
发明人 |
PHIASIVONGSA, PASIT;SEHL, LOUIS, C.;FULLER, WILLIAM, DEAN;LAIDIG, GUY, J. |
分类号 |
C07K5/10;A61K38/06;A61K38/07;A61P19/08;A61P25/28;A61P37/06;C07K5/107 |
主分类号 |
C07K5/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|