发明名称 |
COMPOSITIONS COMPRISING DECITABINE AND TETRAHYDROURIDINE AND USES THEREOF |
摘要 |
Embodiments of compositions and methods for the treatment of blood disorders and malignancies in a subject are described herein. In one embodiment, a composition for the treatment of a blood disorder or a malignancy in a subject comprises decitabine, tetrahydrouridine, and an excipient. In another embodiment, a method for the treatment of a blood disorder or a malignancy in a subject comprises the oral administration of a composition comprising decitabine and tetrahydrouridine. In some examples, the composition may be administered 1-3 times weekly.
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申请公布号 |
US2012225836(A1) |
申请公布日期 |
2012.09.06 |
申请号 |
US201213414546 |
申请日期 |
2012.03.07 |
申请人 |
DESIMONE JOSEPH;SAUNTHARARAJAH YOGEN;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS |
发明人 |
DESIMONE JOSEPH;SAUNTHARARAJAH YOGEN |
分类号 |
A61K31/7072;A61P7/00;A61P35/00;A61P35/02 |
主分类号 |
A61K31/7072 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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