A rabbit model for evaluating vasomotor response which involves measurements of the central ear artery
摘要
Disclosed is a method for evaluating the effect of a compound on vasomotor response in vivo comprises the steps of administering said compound to a rabbit and measuring the diameter of the vessel lumen of a central ear artery of said rabbit in comparison with the baseline diameter of the vessel lumen of said central ear artery of said rabbit, said baseline diameter being measured prior to the administration of said compound.
申请公布号
NZ591942(A)
申请公布日期
2012.08.31
申请号
NZ20090591942
申请日期
2009.10.21
申请人
JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C.
发明人
PARRY, TOM JAY;DAMIANO, BRUCE P;GIARDINO, EDWARD C;CONNELLY, MARGERY A