| 发明名称 |
MODULATION OF SGLT-2 EXPRESSION |
| 摘要 |
Compounds, compositions and methods are provided for modulating the expression of SGLT2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding SGLT2. Methods of using these compounds for modulation of SGLT2 expression and for diagnosis and treatment of diseases and conditions associated with expression of SGLT2 are provided.
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| 申请公布号 |
US2012196921(A1) |
申请公布日期 |
2012.08.02 |
| 申请号 |
US201113300404 |
申请日期 |
2011.11.18 |
| 申请人 |
FREIER SUSAN M.;WANCEWICZ EDWARD;MONIA BRETT P.;SIWKOWSKI ANDREW M.;WATTS LYNNETTA;LEEDOM THOMAS A.;ISIS PHARMACEUTICALS, INC. |
发明人 |
FREIER SUSAN M.;WANCEWICZ EDWARD;MONIA BRETT P.;SIWKOWSKI ANDREW M.;WATTS LYNNETTA;LEEDOM THOMAS A. |
| 分类号 |
A61K31/711;A61K31/70;A61K31/7105;A61K48/00;A61P3/08;A61P3/10;C07H;C07H21/02;C07H21/04;C12N15/11;C12N15/113;C12Q1/68 |
主分类号 |
A61K31/711 |
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