摘要 |
<P>PROBLEM TO BE SOLVED: To provide a highly safe collagen production promotor, a proteoglycan production promotor and a chondrocyte migration promotor. <P>SOLUTION: This invention relates to the collagen production promotor for shoulder tendon tissue, Achilles' tendon tissue, osteoblast and myocyte, wherein the collagen production promotor contains artificial collagen that is a solvent having a concentration of 0.05 to 5.00%(w/v) or an aqueous solution having a concentration of 0.05 to 3.00%(w/v). The artificial collagen comprises peptide units respectively expressed by the following formulae: (1) [-(OC-(CH<SB POS="POST">2</SB>)<SB POS="POST">m</SB>-CO)<SB POS="POST">p</SB>-(Pro-Y-Gly)<SB POS="POST">n</SB>-]<SB POS="POST">a</SB>; (2) [-(OC-(CH<SB POS="POST">2</SB>)<SB POS="POST">m</SB>-CO)<SB POS="POST">q</SB>-(Z)<SB POS="POST">r</SB>-]<SB POS="POST">b</SB>; and (3) [-HN-R-NH-]<SB POS="POST">c</SB>. <P>COPYRIGHT: (C)2012,JPO&INPIT |