发明名称 PHENOLIC HYDRAZONE MACROPHAGE MIGRATION INHIBITORY FACTOR INHIBITORS
摘要 <p>Provided are various compounds of Formula (I): Also provided are pharmaceutical compositions comprising the above compounds. Additionally, methods of inhibiting macrophage migration inhibitory factor (MIF) activity in a mammal are provided, as are methods of treating or preventing inflammation in a mammal. Further provided are methods of treating a mammal having sepsis, septicemia, and/or endotoxic shock. Also provided are methods of treating a mammal having an autoimmune disease, and methods of treating a mammal having a tumor.</p>
申请公布号 EP2004649(B1) 申请公布日期 2012.07.04
申请号 EP20070753868 申请日期 2007.03.23
申请人 THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH 发明人 AL-ABED, YOUSEF
分类号 C07C311/49;A61K31/15;A61K31/18;A61K31/215;A61P29/00;A61P35/00;A61P37/00;C07C251/86;C07C281/02 主分类号 C07C311/49
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