METHOD OF PROCESSING A BIOLOGICAL IMAGE

摘要

A method of processing an image of a biological sample containing nuclei, cytoplasm and micronuclei, each of the nuclei being surrounded by cytoplasm, determines the incidence of micronuclei in the sample. The cytoplasm has a maximum distance, which is the largest extent of the cytoplasm from its nucleus occurring in the image. The method includes the steps of setting a search distance at a value less than the maximum distance, searching for micronuclei within the search distance from the nuclei and annotating the micronuclei found in the search.