发明名称 Cancer therapy using Bcl-XL-specific siNA
摘要 The invention relates to a double-stranded short interfering nucleic acid (siNA) molecule specific to the Bcl-XL transcript, comprising a sense and an antisense region, wherein the sense region comprises the nucleotide sequence SEQ ID NO: 1 or a sequence having at least 70% identity, preferably at least 80% identity, more preferably at least 90% identity with said sequence, and the antisense region comprises a nucleotide sequence that is complementary to the sense region, and its use for treating cancer.
申请公布号 US8193333(B2) 申请公布日期 2012.06.05
申请号 US20070306093 申请日期 2007.06.22
申请人 POULAIN LAURENT;GAUDUCHON PASCAL;BROTIN EMILIE;SAISON-BEHMOARAS ESTER;CENTRE REGIONAL DE LUTTE CONTRE LE CANCER-CENTRE FRANCOIS BACLESSE 发明人 POULAIN LAURENT;GAUDUCHON PASCAL;BROTIN EMILIE;SAISON-BEHMOARAS ESTER
分类号 C07H21/04;A61K48/00;C07H21/02;C12N15/11;C12N15/113 主分类号 C07H21/04
代理机构 代理人
主权项
地址