发明名称 [(2-Carbamotioylhydrazone)propionato(2-)]-(4-aminobenzenesulfonamide)copper, manifesting antimicrobial activity against bacteria of the genus Bacillus cereus
摘要 The invention relates to chemistry and medicine, namely to a coordinative compound of biologically active copper from the class of thiosemicarbazonates.Summary of the invention consists in the synthesis of a new compound of copper with two biologically active ligands [(2-carbamotioylhydrazone)propionato(2-)]-(4-aminobenzenesulfonamide)copper of formula:The compound manifests high bacteriostatic and bactericidal activity against bacteria of the genus Bacillus cereus. Due to these properties it can be used in medicine and veterinary medicine as an antimicrobial drug.The result consists in that the new compound manifests antimicrobial activity against bacteria of the genus Bacillus cereus 33…156 times higher than furacin and approximately 1·105 times higher than the structural analogue - the copper complex with 2-formylpyridine thiosemicarbazone.
申请公布号 MD4133(C1) 申请公布日期 2012.05.31
申请号 MD20100000083 申请日期 2010.07.19
申请人 UNIVERSITATEA DE STAT DIN MOLDOVA 发明人 GULEA AURELIAN;TAPCOV VICTOR;LOZAN-TIRSU CAROLINA;RUDIC VALERIU;&TCEDIL,APCOV VICTOR;LOZAN-TIR&SCEDIL,U CAROLINA
分类号 C07F1/08;A61K31/175;A61K31/30;A61K31/63;A61P31/04;C07C59/19;C07C311/39;C07C337/08 主分类号 C07F1/08
代理机构 代理人
主权项
地址