发明名称 |
Method for detecting the presence of target bacteria or a target component carbohydrate antigen thereof |
摘要 |
A process is disclosed for separating a carbohydrate antigen from a Gram-positive or Gram-negative bacteria in a purified form that contains no more than 10% protein. The separated antigen is coupled to an affinity column, over which polyclonal antibodies to the same bacteria are chromatographed and recovered in a purified form that exhibits high specificity and sensitivity in immunoassays for the raw carbohydrate antigen corresponding to the purified antigen on the column. A particularly preferred form of rapid immunochromatographic assay employing the purified antibodies, which assay is very useful as an aid to rapid diagnosis of diseases caused by bacteria, is disclosed.
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申请公布号 |
US2012135420(A1) |
申请公布日期 |
2012.05.31 |
申请号 |
US20070982400 |
申请日期 |
2007.10.31 |
申请人 |
KOULCHIN VLADIMIR ANDREI;MOORE NORMAN JAMES;MOLOKOVA ELENA VALENTIN;FENT MARY KATHLEEN;BINAX, INC |
发明人 |
KOULCHIN VLADIMIR ANDREI;MOORE NORMAN JAMES;MOLOKOVA ELENA VALENTIN;FENT MARY KATHLEEN |
分类号 |
G01N33/569;C07K1/22;C07K16/12;C12P19/04;G01N33/53 |
主分类号 |
G01N33/569 |
代理机构 |
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地址 |
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