发明名称 |
TARGETED INTERFERON DEMONSTRATES POTENT APOPTOTIC AND ANTI-TUMOR ACTIVITIES |
摘要 |
<p>This invention provides novel chimeric moieties that show significant efficacy against cancers. In certain embodiments the chimeric moieties comprise a targeting moiety attached to an interferon. In certain embodiments, the chimeric moieties comprise fusion proteins where an antibody that specifically binds to a cancer marker is fused to interferon alpha (IFN-±).</p> |
申请公布号 |
EP2200634(A4) |
申请公布日期 |
2012.05.30 |
申请号 |
EP20080831632 |
申请日期 |
2008.09.19 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MORRISON, SHERIE, L.;HUANG, TZU-HSUAN;XUAN, CAIYUN |
分类号 |
A61K38/21;A61K47/48;A61P35/00;C07K16/32;C12N15/62 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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