发明名称 Combination of pilocarpin and methimazol for treating charcot-marietooth disease and related disorders
摘要 Disclosed is a composition comprising pilocarpine and methimazole, or pilocarpine and carbimazole or salts thereof. Also disclosed is a combination product comprising a muscarinic receptor agonist selected from the group consisting of pilocarpine, cevimeline, carbachol, methacholine, and bethanechol and an inhibitor of thyroid hormone synthesis selected from the group consisting of methimazole, carbimazole,propylthiouracil and amiodarone, or a salt thereof, for a grouped or separate administration to a subject, simultaneously or sequentially. The use of the compositions for treating Charcot-Marie Tooth disease is also disclosed.
申请公布号 NZ589940(A) 申请公布日期 2012.05.25
申请号 NZ20090589940 申请日期 2009.06.17
申请人 PHARNEXT 发明人 COHEN, DANIEL;CHUMAKOV, ILYA;NABIROCHKIN, SERGUEI;GUERASSIMENKO, OXANA;CHOLET, NATHALIE
分类号 A61K31/197;A61K31/4164;A61K31/4178;A61K45/06;A61P25/02 主分类号 A61K31/197
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