CANCER DIAGNOSIS KIT AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER

摘要

The present invention relates to a composition for cancer diagnosis having a formulation for measuring the expression level of Chromosome 10 open reading frame 81 (C10orf81) gene mRNA or protein thereof, a kit for cancer diagnosis having the composition, a method for providing information on cancer diagnosis including a step for measuring the expression level of C10orf81 gene mRNA or the expression level of protein coded by the gene, and a method for screening pharmaceutical compositions for the prevention or the treatment of cancer including an expression inhibitor for the C10orf81 gene or an activity inhibitor for the protein thereof, and therapeutic agents for cancer. The present invention enables an accurate diagnosis of cancer by providing genes specific to stomach cancer, liver cancer, colorectal cancer, lung cancer, or prostate cancer, and diagnostic markers for determining the metastasis and prognosis of the cancer, and can be useful in the diagnosis and prognosis management of cancer. Also, the present invention enables the development of new bio-medicines having fewer side effects and customized anticancer drugs by providing a cancer-specific therapeutic agent capable of inhibiting the gene.