MCM6 monoclonal antibodies and methods for their use in the detection of cervical disease,申请号EP20110186380-传众专利搜索

首页产品黄页商标征信

会员服务注册登录

法人/股东/高管

发明名称	MCM6 monoclonal antibodies and methods for their use in the detection of cervical disease
摘要	<p>Compositions and methods for diagnosing high-grade cervical disease in a patient sample are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to MCM6. Monoclonal antibodies having the binding characteristics of an MCM6 antibody of the invention are further provided. Hybridoma cell lines that produce an MCM6 monoclonal antibody of the invention are also disclosed herein. The compositions find use in practicing methods for diagnosing high-grade cervical disease comprising detecting overexpression of MCM6, or both MCM6 and MCM7 in a cervical sample from a patient. Kits for practicing the methods of the invention are further provided. Polypeptides comprising the amino acid sequence for an MCM6 epitope and methods of using these polypeptides in the production of antibodies are also encompassed by the present invention.</p>
申请公布号	EP2455395(A1)	申请公布日期	2012.05.23
申请号	EP20110186380	申请日期	2006.08.10
申请人	TRIPATH IMAGING, INC.	发明人	MALINOWSKI, DOUGLAS P.;FISCHER, TIMOTHY, J.;TAYLOR, ADRIANN, J.
分类号	C07K14/47;C07K16/30;G01N33/574	主分类号	C07K14/47
代理机构		代理人
主权项
地址

您可能感兴趣的专利

Holder for objects of motor vehicle, has housing with wall and opening for access to holding chamber, in which object is accommodated

Motor vehicle, has carriage fixedly connected with base by intermediate piece, fitted on two rails and twisted, so that longitudinal extension of intermediate piece is clamped between rails, where extension is parallel to rails

Pump i.e. gear pump, for common-rail-fuel injection system of internal combustion engine of motor vehicle, has compressible damping element arranged on pressure channel of pump and made of plastic or elastomer

Gas separation arrangement comprises vacuum coating system designed as longitudinally extended flow through system

Chip card for monitoring data integrity and software development integrity, has software module generating software counter-measures and counter-measures relative to redundant data engaged or integrated into components of tool chain

Side window blind for motor vehicle i.e. passenger car, has coupling device arranged outside side window with locking device, and locking device locking end of support bar, where end of support bar lies far from blind web

Lift cylinder i.e. free lift cylinder, for triplex lifting gear of reach fork lift truck, has mechanical pump device attached to shut-off valve device and arranged in piston to convey leakage of agent from air chamber into pressure chamber

Fuel supply device for petrol engine of small two-wheeled vehicle, has housing including tank insertion part that is directly attached into fuel tank to supply fuel in tank by supply connection while insertion part is set to preset pressure

Device for loading and unloading e.g. commercial vehicle, to and from loading space, has hoisting device arranged on chain for conveying goods, where chain includes steering gear for chain links and end that is faced on loading space

Out-of-home media unit has display unit, where control unit is equipped for controlling display on display unit, and has synchronization unit for synchronizing display on display unit

Exhaust system for internal combustion engine of e.g. motor vehicle, has drive motor fastened at support part, which is colder than exhaust gas pipe in region of valve flap during operation of system

Fluid-dynamic bearing system for rotary mounting of stator and rotor in spindle motor, has bearing components mounted relative to each other, and gap filled with fluid and arranged between components, where gap exhibits three openings

Screwing tool e.g. torx, for loosening and fastening screw i.e. commercial screw, has insert arranged in retainer and slightly protruding as stop protection device above front side of tool

Wiping apparatus for cleaning e.g. floor of building, has squeeze device designed like funnel such that cleaning element is compressed during movement in squeeze device in two directions and is wrung out

Cable winch for assembly on e.g. boat deck for transporting loads over loading plane, has extensions formed at support limb and engaged into recess of another support limb such that support limbs are fixed against each other

Rain shield for protecting thighs from rain during cycling, has substructure made of flexible bendable material to cover thighs and held by hook-and-loop fastener, where shield is made of waterproof material/fabric

Ventilation profile, has ventilation openings formed in profile flanges, and connecting line designed as predefined bending edge along which ventilation openings are bent against each other

Label remover for use on surface of e.g. package, has adhesive region formed on side of carrier, where region of carrier includes non-adhering region on side, where carrier is covered in region of adhesive region with protective element

Producing an oxidation-protective-coating and a thermal insulation coating on a substrate exposed to high temperatures, comprises e.g. producing two different powders comprising submicroparticles or nanoparticles

Dachstruktur für ein Cabrioletfahrzeug