METHOD FOR PRODUCING ANTIBODIES USING CANCER CELLS

摘要

The present invention aims to provide a method for antibody preparation. The present invention is directed to a method for preparing an antibody-producing cell, which comprises the following steps:
(1) transplanting metastatic cancer cells capable of expressing a target antigen into a non-human animal to ensure engraftment of the cancer cells in the animal;
(2) immunizing the animal with the target antigen; and
(3) collecting the antibody-producing cell from the immunized animal;
as well as a method for preparing an antibody, which comprises collecting the antibody from the antibody-producing cell prepared by the above method.