IBOPAMINE MALEATE, METHOD FOR PREPARING IT AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

摘要

An ibopamine maleate salt (1:1) is provided which is particularly useful for ophthalmic use for diagnostic and therapeutic purposes. A method for preparing ibopamine maleate (1:1), includes the addition of maleic acid, dissolved in a suitable organic solvent, to ibopamine base, also dissolved in a suitable organic solvent, in a 1:1 molar ratio. An example of a pathological condition that may find benefit from treatment with a pharmaceutical composition containing ibopamine maleate (1:1) is ocular hypotonia.