发明名称 HUMAN SERUM ALBUMIN-SIRNA NANO-SIZED CARRIER SYSTEM
摘要 PURPOSE: A human serum albumin-siRNA delivery system is provided to enhance siRNA delivery efficiency to a target site in vivo and to widely treat various diseases. CONSTITUTION: A human serum albumin-siRNA delivery system has human serum albumin and siRNA. The albumin and siNA has a functional group for connecting the human serum albumin and siRNA by biodegradable covalent bond. The siRNA is a monomer, poly siRNA, or polymer siRNA. The siRNA is a monomer siRNA having 15-30 nucleotide monomer, or a polymer siRNA having 100-600 nucleotides. An anticancer composition contains effective amount of the human serum albumin-siRNA.
申请公布号 KR20120035498(A) 申请公布日期 2012.04.16
申请号 KR20100097038 申请日期 2010.10.05
申请人 KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 发明人 KIM, KWANG MEYUNG;KWON, ICK CHAN;CHOI, KUI WON;YOUN, IN CHAN;HUH, MYUNG SOOK;LEE, SO JIN
分类号 A61K38/38;A61K38/16;C07K14/765;C12N15/113 主分类号 A61K38/38
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