发明名称 |
HUMAN SERUM ALBUMIN-SIRNA NANO-SIZED CARRIER SYSTEM |
摘要 |
PURPOSE: A human serum albumin-siRNA delivery system is provided to enhance siRNA delivery efficiency to a target site in vivo and to widely treat various diseases. CONSTITUTION: A human serum albumin-siRNA delivery system has human serum albumin and siRNA. The albumin and siNA has a functional group for connecting the human serum albumin and siRNA by biodegradable covalent bond. The siRNA is a monomer, poly siRNA, or polymer siRNA. The siRNA is a monomer siRNA having 15-30 nucleotide monomer, or a polymer siRNA having 100-600 nucleotides. An anticancer composition contains effective amount of the human serum albumin-siRNA. |
申请公布号 |
KR20120035498(A) |
申请公布日期 |
2012.04.16 |
申请号 |
KR20100097038 |
申请日期 |
2010.10.05 |
申请人 |
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
KIM, KWANG MEYUNG;KWON, ICK CHAN;CHOI, KUI WON;YOUN, IN CHAN;HUH, MYUNG SOOK;LEE, SO JIN |
分类号 |
A61K38/38;A61K38/16;C07K14/765;C12N15/113 |
主分类号 |
A61K38/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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