发明名称 |
ARYLPYRIMIDINE COMPOUNDS AND COMBINATION THERAPY COMPRISING SAME FOR TREATING CYSTIC FIBROSIS & RELATED DISORDERS |
摘要 |
Provided herein are pharmaceutical compositions comprising an arylpyrimidine compound that modulates the activity of cystic fibrosis transmembrane regulator (CFTR) protein and a second compound that modulates the activity of a CFTR protein. Also provided are methods of treating a disorder associated with CFTR protein function by administering an arylpyrimidine compound that modulates the activity of a CFTR protein and a second compound that modulates the activity of a CFTR protein. The combination therapy can be used to treat, for example, airway inflammation and cystic fibrosis. |
申请公布号 |
WO2011008931(A3) |
申请公布日期 |
2012.04.12 |
申请号 |
WO2010US42103 |
申请日期 |
2010.07.15 |
申请人 |
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC.;CHIANG, PHOEBE;MENSE, MARTIN |
发明人 |
CHIANG, PHOEBE;MENSE, MARTIN |
分类号 |
A01N43/54;A61K31/505 |
主分类号 |
A01N43/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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